Ali Javaheri, MD, PhD is an advanced heart failure and cardiac transplant cardiologist and physician–scientist at Washington University School of Medicine in St. Louis, where he also cares for veterans with heart failure through a dedicated appointment at the St. Louis VA. He completed internal medicine training at Massachusetts General Hospital, followed by cardiology and advanced heart failure/transplant fellowships at the University of Pennsylvania and research fellowships at both Penn and Washington University.

Dr. Javaheri’s research program sits at the intersection of heart failure, metabolism, and proteomics. His lab has helped define how HDL and apolipoprotein M, sphingosine-1-phosphate signaling, autophagy–lysosome pathways, and systemic metabolic stress (including fasting, obesity, diabetes, chemotherapy, and radiation) reshape cardiac and vascular biology. He is PI of an NHLBI R01 on apolipoprotein M as a regulator of myocardial autophagy and leads or co-leads multiple investigator-initiated and industry-sponsored studies in heart failure, cardio-oncology, and GLP-1/SGLT2 biology.

His work has been recognized with the American Society for Clinical Investigation Young Investigator Award, the Jay Cohn Basic Science Young Investigator Award, repeat Northwestern Young Investigator Competition wins (as both fellow and faculty), and the David L. Williams Award from the Kern Lipid Conference; he was also featured in the 50th anniversary issue of Cell highlighting advances and future directions in metabolic and cardiovascular research. Dr. Javaheri is equally committed to mentorship—his trainees have already secured competitive postdoctoral fellowships, national young investigator awards, and have successfully matched into residency, cardiology fellowship, and faculty positions at Washington University, Saint Louis University, and other institutions.