I have over thirty years of experience as a lead biostatistician on large federal grants and have served as a biostatistics leader for numerous research projects and clinical trials. I have authored over 540 peer-reviewed publications and currently serve as the Director of Biostatistics Shared Resources at the Simmons Comprehensive Cancer Center. I possess extensive experience in managing large data sets and in designing and analyzing pre-clinical, clinical, epidemiologic, and laboratory studies. I have also worked on the design and analysis of numerous pre-clinical and laboratory studies. My methodological contributions include numerous papers on the design and analysis of correlated data, such as clustered and repeated measurement data, as well as books like Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research and Design and Analysis of Pragmatic Trials.