EM2511H "Mineralocorticoid Receptors: Evolutionary Mediators of Wound Healing, Turned Harmful by Modern Lifestyle" (IM GR-111425)

Purpose and Overview

This seminar summarizes clinical data linking aldosterone and the mineralocorticoid receptor to atherosclerosis, myocardial infarction, stroke and hypertension and then reviews recent basic science data investigating the molecular mechanisms. 

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Understand the sex-specific role of the endothelial cell mineralocorticoid receptor in atherosclerosis, myocardial infarction and stroke 
  • Understand the role of smooth muscle cell mineralocorticoid receptors in vascular stiffening and blood pressure elevation with aging
  • Understand the diverse roles of aldosterone and the mineralocorticoid receptor in the kidney and blood vessel that mitigate hypotension but when chronically activated, drive cardiovascular disease
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
11/14/2025
Course expires: 
12/31/2025
Cost:
$0.00
Rating: 
0

Photo: First Last, M.D.
Iris Jaffe, M.D., Ph.D.
Elisa Kent Mendelsohn Professor of Molecular Cardiology
Executive Director, Molecular Cardiology Research Institute
Tufts University

Available Credit

  • 1.00 AMA

Price

Cost:
$0.00
Please login or create an account to take this course.

Required Hardware/software

Activities should be run with recent versions of common browsers, including Internet Explorer, Firefox and Google Chrome