David Nguyen completed his PhD in Materials Science and Medical Engineering at MIT in the HST program, where he studied nanoparticle delivery of DNA and RNA to the immune system in the laboratory of Prof. Robert Langer with applications in DNA vaccines and immunostimulatory RNA vaccine adjuvants.  He then went to Stanford University for medical school then moved to UCSF where he completed medical residency and a clinical fellowship in Infectious Diseases.  He is currently an Assistant Adjunct Professor in the DOM Division of Infectious Diseases at UCSF, and is a research fellow of the UCSF CIRM Alpha Stem Cell Clinic working in the laboratory of Prof. Alex Marson.  Dr. Nguyen has clinical interests in treating infections in patients with compromised immune systems including primary immunodeficiencies (PID), and research interests in therapeutic gene editing to correct disease-causing mutations.  Dr. Nguyen has leveraged his background in nucleic acid delivery to create new tools for CRISPR Cas9 genome engineering achieving high-efficiency non-viral gene editing in primary human immune cells, work that has recently been published in Nature Biotechnology and Nature Communications.  He is applying these tools to discover and model mutations associated with PIDs, and he is developing novel strategies for gene correction in human hematopoietic stem cells as a therapeutic platform for treating patients with PID.  Dr. Nguyen is also excited about teaching, and as a first-generation American of mixed ethnicity he is passionate about mentoring and training students historically underrepresented in STEM.