Roscoe Brady, MD, PhD
I am a physician-scientist at Beth-Israel Deaconess Medical Center in Boston. I currently serve as Vice-Chair for research in the BIDMC department of psychiatry and I am an assistant professor at Harvard Medical School. The focus of my research efforts has been to understand how brain circuit dysfunction gives rise to the varied symptoms of psychotic disorders. The goal is to develop a level of understanding that directly informs intervention targeted at pathophysiology. My training began in the MSTP (combined M.D.-Ph.D.) program at Columbia University. I have a background in neurobiology, having completed my Ph.D. thesis in the laboratory of Nobel laureate Richard Axel M.D. I subsequently completed my psychiatry training at the Massachusetts General Hospital-McLean Hospital adult psychiatry residency program. Post-residency I worked in an outpatient clinic and taught, while pursuing research part-time. I received a NIMH K23 award mentored by Matcheri Keshavan MD and Dost Ongur MD-PhD to elucidate the brain circuit pathophysiology of bipolar disorder. I subsequently received an R01 to identify and then target the brain circuits responsible for treatment resistant negative symptoms of schizophrenia. This work uses fMRI imaging to identify the brain substrates of psychotic symptoms and then guide non-invasive neuromodulation to these targets to identify the circuit basis of these symptoms. In addition to my research efforts I supervise a resident teaching clinic and lead the research track of the BIDMC Psychiatry Residency Training Program.
There are no financial relationships to disclose.