EM1612F "Heparin Induced Thrombocytopenia" (IM GR-120916)

Despite the increasing use of direct oral anticoagulants in daily practice, heparin and low molecular weight heparins are still the mainstay of treatment for some patients requiring antithrombotic therapy. Heparin induced thrombocytopenia (HIT) is a complex prothrombotic disorder with a significant morbidity and mortality for the patient. An over-diagnosis or under-diagnosis of HIT and improper management could add to the economic and medico-legal burden on a health system. This presentation discusses the pathophysiology, clinical presentation, diagnostic assays and management of HIT.

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Understand the updates in the pathophysiology of HIT
  • Recognize the different clinical presentations of HIT
  • Use the 4T score to come up with a pretest probability for HIT
  • Order the appropriate diagnostic tests for the diagnosis of HIT
  • Start the initial treatment for HIT and consult hematology for further management
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
Course expires: 

Photo: Srikanth Nagalla, M.D.Srikanth Nagalla, M.D.
Associate Professor of Internal Medicine
Division of Hematology and Oncology

Available Credit

  • 1.00 AMA


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