EM1704D "Interactions of Genes, Environment and the Microbiome in the Epidemic of Diabetes and Metabolic Syndrome" (IM GR-040717)

Obesity, type 2 diabetes and metabolic syndrome are increasing worldwide at epidemic rates.  The purpose of this lecture is to have the audience understand the relationship between these disorders and insulin resistance, and to understand the pathogenetic factors that are contributing to this epidemic.  This will be done by showing how mouse models can mimic many features of the problem and be used to identify the driving forces.  Ultimately, these will be new targets for therapy in the future.

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should know that:

  • Type 2 diabetes, obesity and metabolic syndrome are the results of interactions between genes and the environment, and that different people show different metabolic responses to the same environmental challenges.
  • The gut microbiome in a potentially important integrator of the gene-environment interaction.
  • Identifying the mechanisms underlying these observations can open the potential to new methods of treatment and prevention of these important disorders.
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
Course expires: 

C. Ronald Kahn, M.D.
Chief Academic Officer – Joslin Diabetes Center
Mary K. Iacocca Professor of Medicine - Harvard Medical School
Leonard L. Madison, M.D., Visiting Professorship in Diabetes, Endocrinology and Metabolism

Available Credit

  • 1.00 AMA


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Required Hardware/software

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