EM1803E “Bone Wasn’t Built in a Day: Destruction and Formation of Bone in Rheumatic Diseases.” (IM GR-030218)

This talk will review the impact of inflammation on bone in rheumatic disease, focusing on rheumatoid arthritis (RA) and spondylitis (SpA). Mechanisms of bone erosion and systemic bone loss in RA, as well as bone formation in SpA will be discussed, along with implications for therapy.

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Discuss the importance of osteoclasts and the RANKL/OPG pathway in bone erosion in RA
  • Discuss the role of inflammation in driving bone formation in SpA and the implications for therapy
  • Understand the reasons for the lack of bone repair in rheumatic diseases
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
Course expires: 

Ellen M. Gravallese, M.D.
Professor of Medicine Myles J. McDonough Chair in Rheumatology
Chief, Division of Rheumatology
University of Massachusetts Medical School
Ray A. and Robert L. Kroc Lectureship in Rheumatology

Available Credit

  • 1.00 AMA


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