EM1805H “Diet, the Gut Microbiome, and its Metabolome: Impact on Health and Disease” (IM GR-051818)

The human gut contains a vast number of microorganisms known collectively as the “gut microbiota”. Despite its importance in maintaining the health of the host, growing evidence suggests the gut microbiota may also be an important factor in the pathogenesis of various diseases, a number of which have shown a rapid increase in incidence over the past few decades. In this presentation, I will provide a broad overview of the gut microbiome, the relationship between diet and the production of microbial metabolites, and the role that they play in health and disease. Importantly, I will emphasize not only potential benefits to human health that may result from research focused on the gut microbiome but also the challenges in the field related to the development of practical applications.

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Describe the concept of the “hygiene” hypothesis and why it may be relevant to the rising incidence of diseases associated with industrialization
  • Describe an example by which the gut microbiome utilizes diet to produce metabolites that may have an impact on the development of disease
  • Explain the importance of fecal microbiota transplantation (FMT) in the treatment of disease
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
Course expires: 

Gary D. Wu, M.D.
Professor of Medicine
Ferdinand G. Weisbrod Chair in Gastroenterology
Co-Director, PennCHOP Microbiome Program
Associate Director, Center for Molecular Studies in Digestive and Liver Disease
Perelman School of Medicine – University of Pennsylvania
Visiting Professor hosted by the Division of Digestive and Liver Diseases

Available Credit

  • 1.00 AMA


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