EM1808E "What Does the Kidney Have to Do with It? Renal Perspectives on Non-Renal Solid Organ Transplantation" (IM GR-081018)
Renal dysfunction is an important independent predictor of mortality and graft loss in patients undergoing heart, lung and liver transplantation. Several unique pre-transplant, perioperative and post-transplant risk factors for renal disease exist in this patient population. Pretransplant renal dysfunction will need careful evaluation in potential heart, lung and liver transplant candidates and determination of need for concurrent kidney transplant remains complex. Simultaneous liver kidney and heart-kidney transplant volumes continue to rise in US which may disadvantage the kidney alone transplant recipients in the current allocation. The purpose of this presentation is to describe the prevalence, pathogenesis, risk factors and the clinical management of renal disease pertinent to heart, lung and liver transplant recipients. Evaluation of pretransplant renal dysfunction will be discussed to determine who receives a kidney transplant along with heart, lung and liver transplantation. Impact of rising combined organ transplant volumes on kidney alone transplant list will be discussed. Clinical interventions to lower the burden of renal disease after heart, lung and liver transplant recipients will be outlined.
UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.
At the conclusion of this activity, the participant should be able to:
- Understand the devastating impact of renal dysfunction on mortality and graft loss in heart, lung and liver transplant recipients.
- Understand the pretransplant clinical parameters that will determine the need for kidney transplant along with heart, lung and liver transplantation and limitations of current methods of GFR assessment in pre-transplant candidates.
- Understand the disadvantages to the kidney alone transplant candidates from rising combined organ transplant volumes in US.
- Understand the Post-transplant risk factors for renal disease in heart, lung and liver transplant recipients and management.
Mythili Ghanta, M.D.
Assistant Professor of Internal Medicine
Associate Medical Director Parkland Kidney Transplant Program
Division of Nephrology
Dr. Mythili Ghanta is a transplant nephrologist and joined UT Southwestern in 2016. She finished her transplant nephrology fellowship at Columbia University Medical Center, NY. Prior to joining UT Southwestern, she was an Assistant Professor of Medicine at Wake Forest University School of Medicine, NC and Temple University School of Medicine, PA. Her primary clinical focus includes providing care to kidney transplant recipients as well as managing renal dysfunction in non-renal solid organ transplant recipients. She was the medical director of kidney and pancreas transplant program at Wake Forest University School of Medicine and was instrumental in opening a successful pancreas transplant program at Temple University Medical Center, Philadelphia. She currently serves as the associate medical director of the Parkland Kidney Transplant Program.
- 1.00 AMA