EM2103E "Cardiovascular Precision Medicine and Dynamic Genomes" (IM GR-030521)

The role of germline genetic factors are increasingly identified and characterized for coronary artery disease risk. Acquired genetic mutations in blood cells have recently been recognized as new risk factors for coronary artery disease. Here, we will review the implications of genomic changes from birth onward for the prevention of coronary artery disease.

Target Audience

UT Southwestern faculty, fellows, residents and medical students, community physicians, nurse clinicians, physician assistants and nurses.

Learning Objectives

At the conclusion of this activity, the participant should be able to:

  • Recognize that the heritable basis for coronary artery disease (CAD) may be leveraged to discover causal factors for CAD as well as assist with risk prediction for CAD.
  • Enumerate the diagnostic criteria for clonal hematopoiesis of indeterminate potential (CHIP)
  • Recognize that CHIP is likely a causal risk factor for both hematologic malignancy and CAD.
  • Identify molecularly-guided precision medicine strategies for CAD prevention.
Course summary
Available credit: 
  • 1.00 AMA
Course opens: 
Course expires: 

Pradeep Natarajan, M.D.
Director of Preventive Cardiology, Massachusetts General Hospital
Assistant Professor of Medicine, Harvard Medical School
Associate Member, Broad Institute of Harvard and MIT

Available Credit

  • 1.00 AMA


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