Dr. Tsuji received his MD and PhD from The University of Tokyo. He served his residency in Neurology at Jichi Medical School. In 1984, he moved to NIH and elucidated molecular basis of Gaucher disease. In 1987 he moved to Niigata University, Japan and was appointed as Professor of Neurology and Director at Brain Research Institute, Niigata University. In 2002, he moved to The University of Tokyo as Professor and Chair of Department of Neurology in 2002. He has been involved in exploring molecular basis of not only hereditary neurological diseases but also sporadic neurological diseases by applying cutting-edge technologies of genome analysis. In 2013, his team discovered that COQ2 gene is a susceptibility gene for multiple system atrophy (MSA), which suggested the efficacy of supplementation of a high dose CoQ10 for MSA. Based on this discovery, he has started a clinical trial for MSA.