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ForwardInaugural O'Donnell Brain Institute Symposium: Autism Spectrum Disorders (RP2103C)
Autism spectrum disorder (ASD) is one of the most common neurodevelopmental disorders, affecting one in fifty-five children in the United States. This symposium aims to update the community on new discoveries in the pathophysiology and causes of ASD as well as emerging novel treatments. The symposium will: 1) review novel ways to assess and characterize clinical features of patients with ASD, 2) review neural circuit mechanisms in both humans and animal models of ASD, 3) review insights gained from studying syndromic ASD, and 4) review novel treatments for ASD. Attendees will gain an understanding of the current state of research in the underlying pathophysiology of ASD as well as novel treatments to target those mechanisms.
CLICK HERE FOR E-BROCHURE (Includes )Agenda with Speakers
CLICK HERE FOR POSTER SESSIONS SCHEDULE
Target Audience
This symposium is designed for and open to all involved in autism research and clinical care of Autism Spectrum Disorders.
Learning Objectives
Session 1: To provide knowledge on the clinical phenotyping, genotyping, and biomarker development for ASD.
Session 2: To provide knowledge on the critical neural circuits that contribute to neurodevelopmental disabilities and behavior in ASD.
Session 3: To provide knowledge of the clinical presentation, disease mechanisms and latest research and treatment strategies for syndromic autisms.
Session 4: To provide knowledge on the novel treatments being developed for ASD such as gene replacement therapy, cerebellar circuit modulation, and neuropsychopharmacology.
CLICK HERE FOR CME HANDOUT (agenda, learning objectives, speaker disclosures, and more)
RESOURCES (select an item to access file)
Poster: "A Case Report of Topiramate for Severe Breath Holding Spells in a Patient with Pitt Hopkins Syndrome" - Megan E. Bone, M.D. and Kimberly D. Goodspeed, M.D.
Poster: "An Examination of Implicit Teacher Biases - Kaitlyn Niederstadt, M.S. and Amy Hayes, Ph.D.
References/Bibliography
Abstracts
DAY ONE - Thursday, March 25, 2021
Session 1 addresses the gap in clinical phenotyping, genotyping, and biomarker development in ASD. This session will also address racial disparities that exist in healthcare delivery and clinical research in ASD.
Session 2 addresses the knowledge gap in neural circuit dysfunction in neurodevelopmental disorders, including ASD. It will update attendees on which circuits are involved in ASD and how identified circuit dysfunction may impact behavior.
DAY TWO - Friday, March 26, 2021
Session 3 addresses the knowledge gap in the forms of ASD that are classified as “syndromic” autism that are typically caused by loss of function mutations in single genes. Examples of these are: Fragile X Syndrome, Rett Syndrome, Phelan-McDermid Syndrome and Tuberous Sclerosis. Diagnosis and treatment of the different forms and genetic causes of autism requires clinicians to be educated in their clinical presentation, causes and the latest treatments.
Session 4 addresses the practice gap in novel treatments for ASD such as gene replacement therapy for monogenic forms of ASD, cerebellar circuit modulation, and small molecule and neuropsychopharmacology approaches for ASD.
Session 1: Advancing Assessment and Characterization of Autism
Stephen Scherer, PhD - The Hospital for Sick Children, University of Toronto
Maria Chahrour, MD - UT Southwestern Medical Center
Sarah Webb, PhD - University of Washington, Seattle Children's Research Institute
Jed Elison, PhD - University of Minnesota, Institute of Child Development
Matthew Mosconi, PhD - University of Kansas Center for Autism Research and Training
Patricia Evans, MD, PhD - UT Southwestern Medical Center; Children's Medical Center Dallas
Session 2: Neural Circuit Mechanisms in Autism: Humans and Animal Models
Shafali Jeste, MD - UCLA School of Medicine and Center for Autism Research and Treatment
Lauren Orefice, PhD - Harvard Medical School; Massachusetts General Hospital
Jason Lerch, PhD - Oxford University; Wellcome Centre for Integrative Neuroimaging
Michela Fagiolini, PhD - Harvard Medical School; Boston Children's Hospital
Kimberly Huber, PhD - UT Southwestern Medical Center
Genevieve Konopka, PhD - UT Southwestern Medical Center
Session 3: Insights from Syndromic Autism; Humans and Animal Models
Mustafa Sahin, MD, PhD - Harvard Medical School; Boston Children's Hospital
Ben Philpot, PhD - University of North Carolina, Chapel Hill
Mark Bear, PhD - Massachusetts Institute of Technology; Picower Institute for Learning and Memory
Ype Elgersma, PhD - Erasmus Medical Center, Netherlands
Guoping Feng, PhD – Massachusetts Institute of Technology; McGovern Institute
Session 4: Therapeutic Opportunities for Autism
Steven Gray, PhD - UT Southwestern Medical Center
Kimberly Goodspeed, MD - UT Southwestern Medical Center
Peter Tsai MD, PhD - UT Southwestern Medical Center
Catherine Stoodley, DPhil - American University
Craig Erickson, MD - Cincinnati Chidren's Hospital; University of Cincinnati
Evdokia Anagnostou, MD - Holland Bloorview Kids Rehabilitation Hospital, University of Toronto
ASD Symposium Planning Committee
Kimberly Huber, PhD (Course Director) - UT Southwestern Medical Center
Peter Tsai, MD, PhD - UT Southwestern Medical Center
Patricia Evans, MD, PhD - UT Southwestern Medical Center
Kimberly Goodspeed, MD - UT Southwestern Medical Center
William T. Dauer, MD - Director, Peter O’Donnell Jr. Brain Institute
Vicki Dennis – Associate Vice President, Peter O’Donnell Jr. Brain Institute
Mark Vinciguerra - Program Coordinator, UT Southwestern Office of CME
Accreditation
The University of Texas Southwestern Medical Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Credit Designation
The University of Texas Southwestern Medical Center designates this continuing education activity for a maximum of 14.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
The University of Texas Southwestern Medical Center certifies that non-physicians will receive an attendance certificate stating that they participated in the activity that was designated for a maximum of 14.5 AMA PRA Category 1 Credits™.
Available Credit
- 14.50 AMA
- 14.50 Attendance
Price
THERE IS NO CHARGE TO ATTEND THIS SYMPOSIUM.
To register:
- "Login" to your existing account or create an account in EthosCE, online learning management system, by selecting the "create an account" link.
- Once logged in, return to this course page, select the designated fee and click the "add to cart" button.
- In the following "checkout" pages you will verify and process your payment.
- After registration is completed, a confirmation will be sent by email.
Required Hardware/software
Operating System
- Windows 7 - Windows 10
- Mac OS X 10.9 (Mavericks) - macOS Catalina (10.15)
- Linux
- Google Chrome OS
- Android OS 5 (Lollipop) - Android 9 (Pie)
- iOS 10 - iOS 12
- Windows Phone 8+, Windows 8RT+
Web browser
- Google Chrome (most recent 2 versions)
- Mozilla Firefox (most recent 2 versions
Internet connection
- Computer: 1 Mbps or better (broadband recommended)
- Mobile device: 3G or better (WiFi recommended for VoIP audio)
Software
- GoToWebinar desktop app
- GoToWebinar mobile app
- JavaScript enabled
Hardware
- Microphone and speakers (USB headset recommended)
Mobile device
- iPhone 4S or later
- iPad 2 or later
- Android OS 5 (Lollipop) - Android 9 (Pie)